The Missouri Joint Oversight Task Force (JOTF) for Prescription Drug Monitoring was created in 2021 after passage of SB 63 which was sponsored by Senator Holly Thompson-Rehder and signed by Governor Michael L. Parson. The JOTF is authorized to supervise the collection and use of patient dispensation information for prescribed Schedule II, III, or IV controlled substances as submitted by dispensers.

The JOTF is comprised of six members serving terms not to exceed four years. JOTF members are appointed by their respective state regulatory boards and include two licensed physicians or surgeons from the Board of Healing Arts; two licensed pharmacists from the Board of Pharmacy; one advanced practice registered nurse from the Board of Nursing; and one licensed dentist from the Dental Board.